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Corresponding author: guying, 1137865395@qq.com

DOI: 10.12201/bmr.202507.00051

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  Abstract: Knee osteoarthritis (KOA) is a degenerative joint disease characterized by pain, swelling, and limited mobility, which falls under the category of Bi syndrome in Traditional Chinese Medicine (TCM). Knee Bi syndrome arises from the obstruction of external pathogens in local regions, leading to meridian stagnation and subsequent pain. Prolonged stagnation of local qi movement results in pathological products such as phlegm-turbidity and blood stasis, while impaired circulation of qi, blood, and body fluids fails to nourish tissues, causing malnourishment-related pain. The principle The collaterals should be treated by promoting their patency (Luo Yi Tong Wei Yong), derived from Ye Tianshis collateral disease theory, provides a therapeutic framework for such conditions. This study integrates this theory with clinical practice by applying the empirical formula Self-formulated Juanbi San from Lin Zheng Zhi Nan Yi An (Clinical Guide Medical Case Records). Focusing on collateral-dredging as the primary treatment strategy, this approach aims to propose novel perspectives and methodologies for KOA clinical management.

  Key words: Knee osteoarthritis (KOA); The collaterals should be treated by promoting their patency (Luo Yi Tong Wei Yong); External application of Chinese herbal medicine; Self-formulated Juanbi San

  Submit time: 16 July 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2025-06-29	10.12201/bmr.202507.00051V1	Download

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