Analysis Of Infection Status And Drug Sensitivity Of Mycoplasma And Chlamydia In 2324 Outpatients

Corresponding author: LI Zhi-yu, sophyyy0653@sina.com.cn

DOI: 10.12201/bmr.202504.00025

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  Abstract: Objective To analyze the infection and drug resistance of Ureaplasma urealyticum (UU), Mycoplasma hominis (MH) and Chlamydia Trachomatis (CT) in 2324 outpatients, and to provide reference for the prevention and treatment of nongonococcal infections in urogenital tract. Methods UU and MH were detected by liquid culture method and drug sensitivity tests were carried out, and CT was detected by latex method, and the results were statistically analyzed. Results The total positive rate of 2324 patients submitted for examination was 43.3%, and the positive rate in women was significantly higher than that in men. The positive detection rates of UU, MH and CT were 44.8%, 10.0% and 1.8% respectively. Among patients with single infection, the UU positive detection rate was the highest (31.8%). Among patients with mixed infections, the positive detection rate of UU+MH (8.2%) was the highest. The age groups with the highest positive rates of UU, MH and CT were 41 - 50 years old, ≤20 years old and 21 - 30 years old respectively. Drug sensitivity test results of 981 positive patients showed that UU and MH were highly sensitive to doxycycline, minocycline and josamycin, with the sensitivity rates of 97.2%, 96.9% and 95.4% respectively. Conclusion The patients with nongonococcal infection in urogenital tract in our hospital are mainly young and middle-aged (21-40 years old). UU is the main pathogen detected, and the detection rate of female is higher than that of male. According to the drug sensitivity results of mycoplasma, it is suggested to choose doxycycline, minocycline and josamycin for treatment.

  Key words: ureaplasma urealyticum; mycoplasma hominis; chlamydia trachomatis; sexually transmitted diseases

  Submit time: 9 April 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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