通讯作者: 郑爱华★, 2910629511@qq.com

DOI：10.12201/bmr.202509.00041

Based on The Theory of Lung and Intestine Treatment, The Treatment Experience of Shengxue Tongbian Granules for Acute Lung Injury of Sepsis was explored*

• 摘要：脓毒症急性肺损伤是出现最早且发病率最高的脓毒症并发症,目前尚缺乏有针对性的治疗手段。从中医理论出发,肺与大肠在气血津液、经络、病理传变方面相互影响、相互关联。在脓毒症状态下,急性肺损伤常伴随肠道菌群紊乱及肠道粘膜受损,二者病理生理过程相互交织。生血通便颗粒组方药物具有滋阴通腑之功效,已有研究证实该方具有维护肠黏膜完整性,防止菌群易位,从而改善急性肺损伤的作用。文章立足于“肺肠同治”理论,深入剖析生血通便颗粒治疗脓毒症急性肺损伤的理论依据,为拓宽中医治疗脓毒症急性肺损伤的提供临床新思路。

  关键词： 肺肠同治; 生血通便颗粒; 脓毒症; 急性肺损伤; 滋阴润肠

   

  Abstract: Acute lung injury in sepsis is the earliest and most common complication of sepsis, and there is still a lack of targeted treatment. Starting from the theory of traditional Chinese medicine, the lungs and the large intestine affect and correlate with each other in terms of qi, blood, fluid, meridians, and pathological transmission. In sepsis, acute lung injury is often accompanied by disturbance of the intestinal microbiota and damage to the intestinal mucosa, and the pathophysiological processes of the two are intertwined. Studies have confirmed that Shengxue Tongbian Granules has the effect of maintaining the integrity of the intestinal mucosa, preventing the translocation of microflora, and thus improving acute lung injury. Based on the theory of lung and intestinal treatment, this paper deeply analyzes the theoretical basis of Shengxue Tongbian Granules in the treatment of acute lung injury in sepsis, and provides new clinical ideas for broadening the treatment of acute lung injury in sepsis with traditional Chinese medicine.
  Keywords: Lung and Intestinal Treatment; Shengxue Tongbian Granules; Sepsis; Pulmonary and Intestinal Injury; Nourish yin and moisten the intestines

  Key words: Lung and Intestinal Treatment; Shengxue Tongbian Granules; Sepsis; Pulmonary and Intestinal Injury; Nourish yin and moisten the intestines

  提交时间：2025-09-17

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• 序号	提交日期	编号	操作
  1	2025-07-24	bmr.202509.00041V1	下载

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