刘雪杨, 程柯, 许树才. 非小细胞肺癌患者血液高凝状态治疗研究进展. 2025. biomedRxiv.202506.00015
非小细胞肺癌患者血液高凝状态治疗研究进展
通讯作者: 刘雪杨, 1481160154@qq.com
DOI:10.12201/bmr.202506.00015
Progress in the treatment of blood hypercoagulability in patients with non-small cell lung cancer
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摘要:基于临床数据发现非小细胞肺癌患者普遍存在血液高凝状态,而血液高凝状态会促进疾病进展,并会引起包括静脉血栓栓塞等并发症,是导致患者死亡的重要因素。西医认为造成血液高凝状态的成因复杂多样,有血管内皮损伤、组织因子异常、抗凝及纤溶系统抑制等。中医认为有因虚致瘀、因毒致瘀、七情致瘀、血出致瘀。文章对非小细胞肺癌患者血液高凝状态的发生机制、中医病机及中西医治疗进展做简要综述,为伴有血液高凝状态的非小细胞肺癌患者治疗提供一定参考。
Abstract: Based on clinical data, it is found that non-small cell lung cancer patients generally have hypercoagulable state of blood, and hypercoagulable state of blood promotes disease progression and causes complications including venous thromboembolism, which is an important factor leading to the death of patients. According to Western medicine, the causes of hypercoagulability are complex and varied, including vascular endothelial damage, tissue factor abnormality, inhibition of anticoagulant and fibrinolytic systems, and so on. Chinese medicine believes that there are stasis due to deficiency, stasis due to toxicity, stasis due to seven emotions, and stasis due to blood outflow. The article provides a brief review of the occurrence mechanism of hypercoagulability in non-small cell lung cancer patients, the pathogenesis of Chinese medicine, and the progress of Chinese and Western medicine treatment, so as to provide a certain reference for the treatment of non-small cell lung cancer patients with hypercoagulability.
Key words: Non-small cell lung cancer; hypercoagulable state of blood; treatment; extravasated blood提交时间:2025-06-07
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序号 提交日期 编号 操作 1 2025-05-03 bmr.202506.00015V1
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