郭倩, 马蔚蓉, 陈婕, 杨颖倩, 谈勇. 《济阴纲目·求子门》治疗女子不孕症用药规律探析. 2024. biomedRxiv.202411.00067
《济阴纲目·求子门》治疗女子不孕症用药规律探析
通讯作者: 谈勇, yfy136@njucm.edu.cn
DOI:10.12201/bmr.202411.00067
Study on the rules of medication in treating female Infertility in Jiyin Gangmu·Qiuzimen
Corresponding author: Tan Yong, yfy136@njucm.edu.cn
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摘要:目的 探析《济阴纲目·求子门》治疗女子不孕症的用药规律及组方特色。方法 收集整理《济阴纲目·求子门》中所载治疗女子不孕症的方剂中的所有药物,参照《中华人民共和国药典》及《中药学》规范药物名称后建立Excel数据库。运用中医传承辅助平台(V3.0)对药物使用频次、四气五味、归经、核心配伍等进行统计分析,归纳总结得出《济阴纲目·求子门》治疗女子不孕症的用药规律和组方特色。结果 《济阴纲目·求子门》中治疗女子不孕症的方剂共32首,除“坐导药”、“内药续生丸”两首外用方外,内服方剂共30首,涉及中药94味,其中使用频率最高的药物是当归、川芎、香附、茯苓、熟地黄、白芍、人参、白术等,常用药对有当归与川芎、当归与香附、川芎与香附等,药物功效分类中补虚类最多,活血化瘀类次之,中药四气分布以温、平为主,五味以苦、甘居多,药物归经以肝、脾、肾为主。结论 《济阴纲目·求子门》治疗女子不孕症用药以温补为主,重视脏腑辨证,尤重肝、脾、肾三脏,善用当归、熟地黄、白芍、人参、白术等补益药以养精血,活用川芎、香附、牡丹皮等行气活血药以调经,灵活运用药对,为后世中医临床治疗不孕症提供了重要参考。
关键词: 济阴纲目;求子门;不孕症;药对;Abstract: Objective To explore the medication rules and prescription characteristics of the Ji Yin Gang Mu Qiu Zi Men in the treatment of female infertility. Methods Collect and organize all the drugs in the prescriptions for treating female infertility in the Ji Yin Gang Mu · Qiu Zi Men, and establish an Excel database based on the standardized drug names in the Pharmacopoeia of the Peoples Republic of China and Chinese Materia Medica. Using the Traditional Chinese Medicine Inheritance Assistance Platform (V3.0), statistical analysis was conducted on the frequency of drug use, four qi and five flavors, meridian tropism, core compatibility, etc., and the medication rules and prescription characteristics of the Ji Yin Gang Mu Qiu Zi Men for treating female infertility were summarized and concluded. Results There are a total of 32 prescriptions for treating female infertility in the Ji Yin Gang Mu · Qiu Zi Men. In addition to the two external prescriptions of sitting guide medicine and internal medicine Xu Sheng Wan, there are a total of 30 internal prescriptions, involving 94 traditional Chinese medicines. Among them, the most frequently used medicines are Angelica sinensis, Chuanxiong, Xiangfu, Fuling, Rehmannia glutinosa, Paeonia lactiflora, ginseng, Atractylodes macrocephala, etc. Commonly used medicines include Angelica sinensis and Chuanxiong, Angelica sinensis and Xiangfu, Chuanxiong and Xiangfu, etc. In terms of medicinal efficacy classification, the category of tonifying deficiency is the most common, followed by the category of promoting blood circulation and removing blood stasis. The distribution of the four qi of traditional Chinese medicine is mainly warm and calm, while the five flavors are mostly bitter and sweet. The main meridian regulating medicines are liver, spleen. Conclusion The treatment of female infertility in the Ji Yin Gang Mu · Qiu Zi Men mainly focuses on warming and tonifying the body, emphasizing the differentiation of internal organs, especially the liver, spleen, and kidneys. It makes good use of tonifying drugs such as Angelica sinensis, Shu Di Huang, Bai Shao, ginseng, and Bai Zhu to nourish the essence and blood, and flexibly uses Qi promoting and blood activating drugs such as Chuanxiong, Xiangfu, and Mudan Pi to regulate the meridians. It provides important references for the clinical treatment of infertility in later traditional Chinese medicine.
Key words: Jiyin Gangmu;Qiuzimen; Infertility;Medicine pair提交时间:2024-11-27
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序号 提交日期 编号 操作 1 2024-11-01 bmr.202411.00067V1
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