王上燊, 卢巧. 儿童呼吸道合胞病毒肺炎相关研究进展. 2026. biomedRxiv.202611.00003
儿童呼吸道合胞病毒肺炎相关研究进展
通讯作者: 卢巧, 1124435565@qq.com
DOI:10.12201/bmr.202611.00003
Research on Respiratory Syncytial Virus Pneumonia in Children
Corresponding author: Lu Qiao, 1124435565@qq.com
-
摘要:肺炎是儿童常见多发的呼吸系统疾病,但时至今日仍是导致全球5岁以下儿童住院和死亡的主要原因,严重威胁儿童健康。近年来多项国际研究显示,儿童社区获得性肺炎的病原谱已从细菌为主逐渐转变为以病毒为主导,在病毒性社区获得性肺炎中,呼吸道合胞病毒的检出率居于首位。近年来随着病原检测技术更新、发病机制深入探索及新型预防制剂上市,儿童RSV肺炎的诊疗与防控体系不断完善。本文结合近几年国内外研究成果,从流行病学特征、致病机制、临床诊断、治疗策略、新型预防手段及现存争议与展望进行综述,旨在为儿童RSV肺炎规范化诊疗及早期防控提供循证依据。
Abstract: Pneumonia is a common and prevalent respiratory disease in children, and it remains a leading cause of hospitalization and mortality among children under five years of age worldwide, posing a serious threat to pediatric health. Multiple international studies in recent years have demonstrated that the pathogen spectrum of childhood community-acquired pneumonia (CAP) has gradually shifted from bacterial predominance to viral predominance. Among viral community-acquired pneumonia cases, respiratory syncytial virus (RSV) exhibits the highest detection rate. With advances in pathogen detection technologies, in-depth investigations into pathogenesis, and the launch of novel preventive agents in recent years, the diagnosis, treatment, prevention and control system for pediatric RSV pneumonia has been continuously improved. Based on domestic and international research findings published in recent years, this review summarizes epidemiological characteristics, pathogenic mechanisms, clinical diagnosis, therapeutic strategies, innovative preventive approaches, as well as existing controversies and prospects, aiming to provide evidence-based references for standardized diagnosis, treatment, and early prevention and control of pediatric RSV pneumonia.
Key words: Respiratory syncytial virus; Pneumonia; Children; Research progress提交时间:2026-11-03
版权声明:作者本人独立拥有该论文的版权,预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。 -
图表
-
赵仁兵, 王楠, 李玲艳, 杨艳辉, 高芳芳, 杨梅, 齐爱霞, 陈莉萍. 2020-2022年淄博地区儿童呼吸道病原体检出情况分析. 2025. doi: 10.12201/bmr.202504.00019
牟洪林, 陈剑秋. 光动力疗法及复发性呼吸道乳头状瘤病的研究进展. 2024. doi: 10.12201/bmr.202410.00009
刘嘉欣, 张小华, 杨逸彤. CARDS TX在儿童肺炎支原体感染中的研究进展. 2025. doi: 10.12201/bmr.202506.00057
田锋, 张建明, 史燕, 孙玉婷, 夏侯为民, 耿合员, 卢耀勤. 呼吸道病原体高通量快速检测技术研究进展. 2024. doi: 10.12201/bmr.202409.00061
张迎欣, 刘汝洋, 张国鹏, 孙洪唯, 房振胜. IL-37在呼吸系统疾病中的研究进展. 2025. doi: 10.12201/bmr.202501.00038
李辉, 邵洁. 儿童孤独症谱系障碍相关环境因素研究进展. 2024. doi: 10.12201/bmr.202410.00005
郭蓉, 马若秋, 纪海霞, 徐长莉, 孙士波, 李敏, 肖创, 杨为民. 呼吸疾病中炎症消退分子机制及防治策略研究进展. 2026. doi: 10.12201/bmr.202602.00033
p>何海玲, 陆建良, 冯媛, 卢艳玲. 儿童重症肺炎支原体肺炎的临床特点分析. 2025. doi: 10.12201/bmr.202505.00038
吴思乐, 曾韵萍, 刘晖, 龚璇, 陆丹红. 耳尖刺络放血联合柴葛解肌汤治疗急性上呼吸道病毒感染性发热的疗效观察. 2026. doi: 10.12201/bmr.202602.00089
吴军良. 中性粒细胞CD64指数、CRP、IL-6与PCT水平在病毒性和细菌性呼吸道感染中的诊断价值. 2024. doi: 10.12201/bmr.202412.00064
-
序号 提交日期 编号 操作 1 2026-10-16 10.12201/bmr.202611.00003V1
下载 -
-
公开评论 匿名评论 仅发给作者
引用格式
访问统计
- 阅读量:33
- 下载量: 0
- 评论数:0

登录
注册




京公网安备