施欣彤, 陈煜, 盛常睿. 多模态直肠腔内超声在直肠癌分期中的应用进展. 2026. biomedRxiv.202610.00055
多模态直肠腔内超声在直肠癌分期中的应用进展
通讯作者: 盛常睿
DOI:10.12201/bmr.202610.00055
Progress in the Application of Multimodal Endorectal Ultrasound for Staging of Rectal Cancer
Corresponding author: Sheng Changrui
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摘要:直肠癌是世界上常见的消化道恶性肿瘤之一,其发病率与死亡率在我国均位居前列。准确的术前分期是直肠癌个体化、精准化治疗的基础,而传统的影像学方法在早期直肠癌分期方面存在一定不足。直肠腔内超声(ERUS)凭借便携、实时、无创、可重复性高等优势,在直肠癌分期中受到广泛关注,近年来更通过与对比增强超声、超声弹性成像、三维超声及超微血流成像等技术的融合,逐步发展为多模态、多参数的评估体系。本文从ERUS在T分期与N分期中的应用、不同超声技术的价值以及人工智能与影像组学的融合等方面,介绍多模态直肠腔内超声在直肠癌分期中的应用进展,希望能为直肠癌的精准分期与临床诊疗提供参考。
Abstract: Rectal cancer is one of the most common gastrointestinal malignancies worldwide, and both its incidence and mortality rates remain among the leading causes in China. Accurate preoperative staging is the foundation for individualized and precision treatment of rectal cancer. However, conventional imaging modalities have certain limitations in the staging of early-stage disease. Endorectal ultrasound (ERUS), with its advantages of portability, real-time imaging, noninvasiveness, and high repeatability, has attracted increasing attention for rectal cancer staging. In recent years, ERUS has evolved into a multimodal and multiparametric assessment framework through integration with contrast-enhanced ultrasound, ultrasound elastography, three-dimensional ultrasound, and microvascular flow imaging, among other techniques. This article reviews the applications of multimodal ERUS in T and N staging, summarizes the clinical value of different ultrasound modalities, and discusses the integration of artificial intelligence and radiomics. The aim is to provide a reference for more precise tumor staging and clinical decision-making in rectal cancer.
Key words: Rectal Cancer; Endorectal Ultrasound; Multimodal Ultrasound; Elastography; Tumor Staging提交时间:2026-10-26
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序号 提交日期 编号 操作 1 2026-09-18 10.12201/bmr.202610.00055V1
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