张冉冉. 2014-2024年天津市某儿童医院住院儿童糖尿病发病趋势. 2026. biomedRxiv.202605.00061
2014-2024年天津市某儿童医院住院儿童糖尿病发病趋势
通讯作者: 张冉冉, zhangranran0502@163.com
DOI:10.12201/bmr.202605.00061
Trends in the incidence of diabetes mellitus among hospitalized children in a childrens hospital in Tianjin, 2014–2024
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摘要:目的 分析2014年-2024年间天津市某儿童医院住院儿童糖尿病的流行病学特征以及发展趋势,为儿童糖尿病防治提供依据。方法 收集该院2014年1月1日-2024年12月31日所有糖尿病住院儿童的首诊报告数据,采用描述性流行病学分析方法对发病患儿的发病时间、糖尿病类型、年龄组、性别、地区分布进行分析,使用 joinpoint 回归分析方法,以年份为自变量、糖尿病发病人数为因变量,分析儿童糖尿病及在不同人群间的流行趋势。结果 天津市某儿童医院2014年-2024年间糖尿病住院患儿中天津地区发病患儿为885例,10年间发病人数整体呈上升趋势(APC=7.83*),其中1型糖尿病391例,2型糖尿病235例,2型糖尿病患儿发病人数呈上升趋势(APC=27.36*);男性451例,女性434例,发病人数整体均呈上升趋势(APC 值分别为 10.12* 和 5.56*);学龄期年龄段患儿占比最高,为473例,学龄期和青春期糖尿病患儿发病人数均呈上升趋势(APC 值分别为 7.95* 和 8.95*);地区分布中,以滨海新区发病人数最多。结论 2014-2024年间该院住院儿童糖尿病发病人数整体呈上升趋势,其中1型糖尿病的2014-2017年间及2型糖尿病10年间发病趋势与整体趋势大致相符;不同性别、学龄期和青春期年龄组的糖尿病发病趋势与整体发病趋势大致相符, Joinpoint 回归模型可揭示不同人群间糖尿病发病患儿的流行趋势特征,为提升儿童糖尿病防治水平提供科学依据。
Abstract: Objective To analyze the epidemiological characteristics and developing trends of hospitalized children with diabetes in a children’s hospital in Tianjin from 2014 to 2024, so as to provide evidence for the prevention and treatment of childhood diabetes.Methods The initial diagnosis data of all hospitalized children with diabetes admitted to the hospital from January 1, 2014 to December 31, 2024 were collected. Descriptive epidemiological methods were adopted to analyze the onset time, diabetes classification, age groups, gender and regional distribution of sick children. With year as the independent variable and the number of diabetic cases as the dependent variable, Joinpoint regression analysis was applied to explore the epidemiological trends of childhood diabetes among different populations.Results A total of 885 hospitalized children with diabetes from Tianjin were enrolled in this hospital during 2014-2024. The overall number of cases showed an upward trend with an annual percentage change (APC) of 7.83*. There were 391 cases of type 1 diabetes and 235 cases of type 2 diabetes, and the number of children with type 2 diabetes increased obviously with APC of 27.36*. Among all subjects, 451 were boys and 434 were girls, both presenting rising trends with APC of 10.12* and 5.56* respectively. School-age children accounted for the largest proportion with 473 cases. The case numbers of school-age and adolescent children both showed increasing trends, with APC of 7.95* and 8.95*. In terms of regional distribution, Binhai New Area had the largest number of diabetic children.Conclusion The overall number of hospitalized children with diabetes in this hospital increased steadily from 2014 to 2024. The incidence trend of type 1 diabetes during 2014-2017 and type 2 diabetes within the ten years were basically consistent with the overall trend. Diabetic trends of different genders, school-age and adolescent groups were in line with the general tendency. The Joinpoint regression model can clarify the epidemiological characteristics of childhood diabetes among diverse populations, and offer scientific reference for improving the prevention, control and clinical management of childhood diabetes.
Key words: Childhood diabetes; Epidemiological characteristics; Joinpoint regression提交时间:2026-05-18
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序号 提交日期 编号 操作 1 2026-04-14 10.12201/bmr.202605.00061V1
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