张莹, 张峰, 乔琳, 张月林, 侯忠臣. 经脐单孔腹腔镜在妊娠合并卵巢畸胎瘤中的应用优势分析. 2026. biomedRxiv.202604.00179
经脐单孔腹腔镜在妊娠合并卵巢畸胎瘤中的应用优势分析
通讯作者: 张峰, ZhangFeng16@zzu.edu.cn
DOI:10.12201/bmr.202604.00179
Analysis on the Advantages of Transumbilical Single-Port Laparoscopy in the Treatment of Pregnancy Complicated with Ovarian Teratoma
Corresponding author: Zhangfeng, ZhangFeng16@zzu.edu.cn
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摘要:目的:本研究通过比较经脐单孔腹腔镜手术(TU-LESS)、传统开腹手术及保守治疗的临床疗效,探讨分析经脐单孔腹腔镜在妊娠合并卵巢畸胎瘤中的临床应用价值。方法:收集郑州大学第三附属医院妇科病区2019年1月至2025年1月期间收治的143例妊娠合并卵巢畸胎瘤患者的临床资料,制定严格的纳排标准,根据治疗方式分为单孔腹腔镜组(49例)、开腹组(60例)及保守治疗组(34例)。对三组患者的临床资料进行统计学分析。结果:进行手术的两组患者在年龄、BMI、盆腔手术史、畸胎瘤最大直径、妊娠次数、分娩次数、手术孕周比较,差异均无统计学意义(P>0.05);单孔腹腔镜组术中出血量、术后血红蛋白下降程度、术后住院时间、术后肛门排气时间、术后PSAS瘢痕评分、切口美容满意度等方面明显优于开腹组(P<0.05)。三组无一例失访,均随访至妊娠终止。三组患者妊娠结局比较,足月分娩率差异无统计学意义(P>0.05)。两手术组间剖宫产率差异无统计学意义(P>0.05)。结论:妊娠合并卵巢畸胎瘤行经脐单孔腹腔镜手术具有术中出血量少、切口小、住院时间短的优点,且安全、可行,不影响妊娠结局,可作为妊娠合并卵巢畸胎瘤治疗优先选择的治疗方式。
Abstract: Objective: This study aimed to compare the clinical efficacy of transumbilical single-port ,laparoscopic surgery (TU-LESS), conventional laparotomy, and conservative treatment, and to explore the clinical value of transumbilical singleport laparoscopy in the management of ovarian teratoma in pregnancy. Methods: Clinical data were collected from 143 pregnant patients with ovarian teratoma admitted to the Department of Gynecology, the Third Affiliated Hospital of Zhengzhou University between January 2019 and January 2025. Strict inclusion and exclusion criteria were applied. Patients were divided into three groups according to treatment modality: the single?site laparoscopic group (49 cases), the laparotomy group (60 cases), and the conservative treatment group (34 cases). Clinical data among the three groups were statistically analyzed. Results: There were no statistically significant differences in age, BMI, history of pelvic surgery, maximum diameter of teratoma, number of pregnancies, number of deliveries, and gestational age at surgery between the two surgical groups (P>0.05). The TU?LESS group was significantly superior to the laparotomy group in terms of intraoperative blood loss, postoperative decrease in hemoglobin, postoperative hospital stay, time to first flatus, postoperative PSAS scar score, and patient satisfaction with incision cosmetic outcome (P<0.05). No patients were lost to follow?up in any of the three groups, and all were followed up until the end of pregnancy. There was no statistically significant difference in the term delivery rate among the three groups (P>0.05). There was no statistically significant difference in the cesarean section rate between the two surgical groups (P>0.05). Con-clusion: Transumbilical single-port laparoscopic surgery is a safe and feasible primary treatment option for ovarian teratoma in pregnancy. It offers the distinct advantages of reduced intraoperative blood loss, minimal incision, and shorter hospital stays, without compromising maternal or fetal outcomes.
提交时间:2026-04-29
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序号 提交日期 编号 操作 1 2026-03-11 10.12201/bmr.202604.00179V1
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