• 国家药监局综合司 国家卫生健康委办公厅
  • 国家药监局综合司 国家卫生健康委办公厅

基于数据挖掘技术分析腰痹病的临床用药规律

通讯作者: 刘晓岚, 13627489118@163.com
DOI:10.12201/bmr.202512.00046
声明:预印本系统所发表的论文仅用于最新科研成果的交流与共享,未经同行评议,因此不建议直接应用于指导临床实践。

Analysis of Clinical Medication Patterns for Lumbar Arthralgia Syndrome Based on Data Mining Technique

Corresponding author: LiuXiaoLan, 13627489118@163.com
  • 摘要:目的:基于数据挖掘技术分析腰痹病的临床用药规律。方法:收集湖南中医药大学第二附属医院谢教授门诊病历199则,处方199首,涉及中药149味,运用古今医案云平台(V2.3.5)进行药物频次、属性、归经、关联规则及聚类分析。结果:高频药物包括当归、盐杜仲、川芎等;药性以温(22.05%)、平(17.02%)为主,药味以甘(36.7%)、辛(25.14%)、苦(23.5%)为主;归经多属肝(30.22%)、脾(28.66%)、肾(27.25%)经。核心功效集中于强筋骨、补肝肾、活血止痛。关联规则分析获得46组常用药对,聚类分析提取4类核心药组。结论:谢教授治疗腰痹病强调以补肝肾、强筋骨治其本,以活血止痛、通经活络治其标,体现了其整体调节与标本兼治的学术原则。

    关键词: 腰痹病;数据挖掘;用药规律;谢义松

     

    Abstract: Objective:To analyze the clinical medication patterns for lumbar arthralgia syndrome (Bi syndrome) using data mining techniques.Methods:A total of 199 outpatient medical records and corresponding prescriptions (involving 149 distinct Chinese herbal medicines) from Professor Xies clinic at the Second Affiliated Hospital of Hunan University of Chinese Medicine were collected. The Ancient and Modern Medical Case Cloud Platform (V2.3.5) was employed to conduct analyses on herb frequency, properties, meridian tropism, association rules, and clustering.Results:The high-frequency herbs included Dang Gui (Angelicae Sinensis Radix), Yan Du Zhong (Eucommiae Cortex Praeparata Cum Sal), and Chuan Xiong (Chuanxiong Rhizoma). Herb properties were predominantly warm (22.05%) and neutral (17.02%). The main herb flavors were sweet (36.7%), pungent (25.14%), and bitter (23.5%). The primary meridian tropisms were the Liver (30.22%), Spleen (28.66%), and Kidney (27.25%) meridians. The core therapeutic effects focused on strengthening bones and muscles, tonifying the Liver and Kidney, and promoting blood circulation to relieve pain. Association rule analysis identified 46 groups of commonly used herb pairs, and cluster analysis extracted 4 core herb groups. Conclusion: Professor Xies treatment for lumbar arthralgia syndrome emphasizes treating the root cause by tonifying the Liver and Kidney and strengthening bones and muscles, while addressing the symptoms by promoting blood circulation to relieve pain and activating meridians and collaterals. This approach reflects his academic principle of holistic regulation and simultaneous treatment of both the root and symptoms.

    Key words: Lumbar Paralysis; Data mining; Medication rule; XieYiSong

    提交时间:2025-12-16

    版权声明:作者本人独立拥有该论文的版权,预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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  • 序号 提交日期 编号 操作
    1 2025-11-14

    10.12201/bmr.202512.00046V1

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刘涛, 刘晓岚, 谢义松. 基于数据挖掘技术分析腰痹病的临床用药规律. 2025. biomedRxiv.202512.00046

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