通讯作者: 郑秀丽, 345169343@qq.com

DOI：10.12201/bmr.202511.00010

Observation of the Clinical Efficacy of Repetitive Transcranial Magnetic Stimulation in the Treatment of Functional Constipation

• 摘要：目的：探究磁刺激治疗功能性便秘的疗效。方法：选取2022年3月至2023年3月在南京市中医院肛肠科门诊接受诊治的60例FC患者。随机分为试验组和对照组，每组各30例。实验组将线圈纵轴与头颅呈45°角，对照组将线圈纵轴与头颅呈90°角，进行磁刺激。对比两组患者的评价量表、HRAM相关指标。结果：实验组治疗前后PAC-QOL、CSS、HAMA、HAMD均有统计学意义（P<0.05），对照组治疗前后PAC-QOL、CSS、HAMA、HAMD均无统计学意义（P>0.05）。实验组AMSP、FSV和MTV有统计学意义（P＜0.05）；ARP无统计学意义（P＞0.05）。对照组仅有FSV有统计学意义（P<0.05），其余均无统计学意义。实验组RAIR、RAIR松弛率、RAIR松弛时间均有统计学意义（P<0.05），RAIR残余压无统计学意义（P＞0.05）。结论：磁刺激治疗功能性便秘疗效确切，能缓解患者的临床症状，提升精神状态，改善HRAM相关指标，值得推广。

  关键词： 功能性便秘，磁刺激，高分辨率肛门直肠测压; ; 

   

  Abstract: Objective: To explore the efficacy of magnetic stimulation in the treatment of functional constipation. Methods: A total of 60 FC patients were selected from March 2022 to March 2023 who were diagnosed and treated in the outpatient clinic of the Department of Proctology of Nanjing Hospital of Traditional Chinese Medicine. They were randomly divided into experimental group and control group, with 30 cases in each group. The experimental group performed magnetic stimulation by placing the longitudinal axis of the coil at a 45° angle to the head, while the control group placed the vertical axis of the coil at a 90° angle to the skull. The evaluation scales and HRAM-related indicators of the two groups were compared. Results: The PAC-QOL, CSS, HAMA and HAMD were statistically significant before and after treatment in the experimental group (P<0.05), while the PAC-QOL, CSS, HAMA and HAMD in the control group were not statistically significant before and after treatment (P>0.05). AMSP, FSV and MTV were statistically significant in the experimental group (P<0.05), and ARP was not statistically significant (P>0.05). Only FSV was statistically significant in the control group (P<0.05), and the rest were not statistically significant. The RAIR, RAIR relaxation rate and RAIR relaxation time were statistically significant in the experimental group (P<0.05), and there was no statistically significant RAIR residual pressure (P>0.05). Conclusion: Magnetic stimulation in the treatment of functional constipation has a definite efficacy, which can relieve clinical symptoms, improve mental state, and improve HRAM-related indicators, which is worthy of promotion.

  Key words: functional constipation; magnetic stimulation; high-resolution anorectal manometry

  提交时间：2025-11-05

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
• html

• 图表

• 刘静. 浅析“津血同源”理论治疗女性功能性便秘临床经验. 2025. doi: 10.12201/bmr.202508.00034

  李晶晶, 邱纪方, 周沛华, 曾倩倩, 胡瀚尹. 经颅直流电刺激在中风患者吞咽功能康复中的应用与效果评估. 2024. doi: 10.12201/bmr.202411.00060

  任志源, 陈婕, 杨舒月. 基于“治中焦如衡”探讨半夏泻心汤治疗功能性消化不良的作用机制. 2025. doi: 10.12201/bmr.202508.00032

  艾丽菲热·阿不都热西提, 彭颜晖. 经颅磁刺激治疗脑卒中后失眠的机制与临床研究进展. 2025. doi: 10.12201/bmr.202507.00023

  刘菲菲. 调肠针法联合火龙罐治疗老年脑卒中后便秘的疗效观察. 2025. doi: 10.12201/bmr.202503.00075

  袁清清, 李通, 卿艳平. 直肠低敏在慢性便秘中的研究进展. 2025. doi: 10.12201/bmr.202501.00005

  孔德舜, 付金香. 理气法在治疗老年性便秘中的应用. 2024. doi: 10.12201/bmr.202410.00041

  何贤标, 徐杰, 赵云珍. 数字化模板联合有限切开治疗踝关节骨折的临床疗效观察. 2025. doi: 10.12201/bmr.202501.00083

  袁胜超, 谭志超, 李征, 林馥纯, 吴云飞. 四柱理念治疗SchatzkerⅠ-Ⅳ型胫骨平台骨折的临床疗效观察. 2024. doi: 10.12201/bmr.202411.00018

  刘梦雅, 刘明月, 方明珠, 陈珂, 张艺伸, 王茜, 靳沙沙, 武亮, 李哲. 经颅磁刺激在脑损伤后意识障碍的临床研究进展. 2024. doi: 10.12201/bmr.202411.00033

• 序号	提交日期	编号	操作
  1	2025-09-21	10.12201/bmr.202511.00010V1	下载

• 公开评论  匿名评论  仅发给作者 提交评论