李彤, 孙梦颖, 王俪臻, 赵辉, 刘春龙, 扈有芹, 崔友祥. 基于古今医案云平台探究国医大师治疗慢性头晕的用药组方规律. 2025. biomedRxiv.202511.00001
基于古今医案云平台探究国医大师治疗慢性头晕的用药组方规律
通讯作者: 崔友祥, heartiwing1985@163.com
DOI:10.12201/bmr.202511.00001
Corresponding author: Cui Youxiang, heartiwing1985@163.com
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摘要:目的:基于古今医案云平台,分析国医大师治疗慢性头晕的用药组方规律,总结其临床学术思想。方法:收集2015年12月至2024年9月诊治慢性头晕的初诊处方367首。采用古今医案云平台(V2.3.5)对处方中药物的使用频次、性味归经、功效分布进行统计,并运用关联规则、聚类分析及复杂网络挖掘其核心药对与组方结构。结果:研究结果显示,367首处方涉及中药432味,总使用频次6212次。高频药物(频次≥100)共14味,前10位依次为柴胡(71.39%)、炙甘草(68.66%)、法半夏(58.58%)、白芍(48.77%)、煅牡蛎(44.96%)、人参(44.14%)、桂枝(44.14%)、当归(42.78%)、茯苓(41.42%)、黄芪(41.14%)。药性以温、微寒为主,药味以甘、辛、苦为主,主归脾、肺、肝经。核心功效为燥湿化痰、升举阳气、生津养血。关联规则分析得出柴胡-炙甘草、法半夏-柴胡等高置信度药对;聚类分析得到6个有效药物组合(如茯苓-陈皮燥湿化痰,煅牡蛎-炒黄芩-柴胡-法半夏和解少阳等);复杂网络分析提炼出由柴胡、炙甘草、法半夏等12味药组成的核心处方。结论:慢性头晕病机总属本虚标实,与肝、脾功能失调及少阳枢机不利密切相关。其治疗以从肝论治为核心,强调调和气血、斡旋少阳枢机,并注重痰瘀同治。在方剂运用上善于经方与时方灵活化裁,如以小柴胡汤、黄芪桂枝五物汤等为基础加减,形成了特色鲜明的辨治体系,为临床治疗慢性头晕提供了重要参考。
Abstract: ?:?Objective?: To explore the medication rules and academic thoughts of National Master of Chinese Medicine Professor Wang Qingguo in treating chronic dizziness based on the Ancient and Modern Medical Case Cloud Platform.Methods: A total of 367 initial prescriptions for chronic dizziness treated by Professor Wang Qingguo from December 2015 to September 2024 were collected. The Ancient and Modern Medical Case Cloud Platform (V2.3.5) was used to statistically analyze the frequency, properties, flavors, meridian tropisms, and efficacy distribution of the herbs. Association rule analysis, cluster analysis, and complex network analysis were employed to mine the core herb pairs and formula structures.Results: The 367 prescriptions involved 432 traditional Chinese medicines, with a total frequency of 6,212 times. There were 14 high-frequency herbs (frequency ≥100). The top 10 herbs were Bupleurum (71.39%), Honey-fried Licorice (68.66%), Prepared Pinellia (58.58%), White Peony Root (48.77%), Calcined Oyster Shell (44.96%), Ginseng (44.14%), Cinnamon Twig (44.14%), Chinese Angelica (42.78%), Poria (41.42%), and Astragalus Root (41.14%). Herb properties were mainly warm and slightly cold; flavors were predominantly sweet, pungent, and bitter; the herbs primarily entered the spleen, lung, and liver meridians. The core efficacies were drying dampness and resolving phlegm, lifting yang qi, and promoting fluid production to nourish blood. Association rule analysis identified high-confidence herb pairs such as Bupleurum-Honey-fried Licorice and Prepared Pinellia-Bupleurum. Cluster analysis yielded 6 effective herb combinations (e.g., Poria-Tangerine Peel for drying dampness and resolving phlegm; Calcined Oyster Shell-Baked Scutellaria Root-Bupleurum-Prepared Pinellia for harmonizing Shaoyang). Complex network analysis extracted a core prescription composed of 12 herbs, including Bupleurum, Honey-fried Licorice, and Prepared Pinellia. Conclusion: Professor Wang Qingguo believes that the pathogenesis of chronic dizziness is fundamentally characterized by deficiency with excess manifestation, closely related to dysfunction of the liver and spleen, and impairment of the Shaoyang pivot. His treatment strategy focuses on regulating the liver as the core, emphasizing harmonizing qi and blood, mediating the Shaoyang pivot, and addressing both phlegm and blood stasis. He is skilled in the flexible modification and combination of classical and contemporary formulas, such as using Modified Minor Bupleurum Decoction (Xiao Chaihu Tang) and Astragalus and Cinnamon Twig Five Substances Decoction (Huangqi Guizhi Wuwu Tang) as the basis for modification, forming a distinctive syndrome differentiation and treatment system that provides an important reference for the clinical treatment of chronic dizziness.
Key words: Wang Qingguo; Chronic dizziness; Medication rule; Data mining; Ancient and Modern Medical Case Cloud Platform; Academic thoughtas the academic philosophy of Professor Wang Qingguo in treating chronic dizziness, using the Gujin Medical Case Cloud Platform software.提交时间:2025-11-01
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序号 提交日期 编号 操作 1 2025-10-19 10.12201/bmr.202511.00001V1
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