Research progress on alignment in total knee arthroplasty

Corresponding author: Li Jizheng, carolmiaozz@sina.com

DOI: 10.12201/bmr.202509.00070

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  Abstract: :The alignment relationship serves as a pivotal factor influencing the kinematic performance and clinical outcomes of total knee arthroplasty, ultimately impacting the quality of postoperative rehabilitation for patients with knee osteoarthritis. Establishing a safe, reliable, and stable alignment is crucial for medical personnel when planning surgical protocols and treatment strategies. Currently, a variety of alignment techniques are extensively utilized in total knee arthroplasty, encompassing kinematic alignment, mechanical alignment, anatomical alignment, adjusted mechanical alignment, restricted kinematic alignment, functional alignment, and inverse kinematic alignment. These techniques exhibit distinct advantages in terms of alignment accuracy and force line preservation, among other aspects. In light of this, this article provides an overview of these commonly employed alignment techniques, aiming to offer data support and guidance for research directions in selecting intraoperative alignment relationships for patients with knee osteoarthritis.

  Key words: Total Knee Arthroplasty; Knee Osteoarthritis; Alignment Relationship

  Submit time: 30 September 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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  1	2025-09-01	10.12201/bmr.202509.00070V1	Download

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