The prophylactic value of electroacupuncture combined with antithrombotic compression banding for DVT in neurocritical care patients at high risk for VTE

Corresponding author: Sun Hui, 19905839558@163.com

DOI: 10.12201/bmr.202503.00088

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  Abstract: Objective To investigate the prophylactic value of electroacupuncture combined with antithrombotic compression taping for deep vein thrombosis (DVT) in neurocritical high risk venous thromboembolism (VTE) patients.Methods Ninety-eight cases of high-risk VTE patients with neurocritical illness admitted from April 2023 to May 2024 were selected and divided into 49 cases using random number table method. Both groups were given low molecular heparin calcium to prevent thrombosis, the pressure band group was given antithrombotic pressure band intervention, and the electro-acupuncture group was combined with electro-acupuncture intervention on the basis of antithrombotic pressure band, and the treatment was continued for 14 d. D-dimer (D-D), interleukin-6 (IL-6), fibrinogen (FIB), intercellular adhesion molecule-1 (ICAM-1), activated partial thromboplastin time (APT), and activated partial thromboplastin time (APT) were measured in the patients in the two groups before the treatment, as well as in those who received the treatment for 7d and 14d. ), activated partial thromboplastin time (APTT), tumor necrosis factor-α (TNF-α), and prothrombin time (PT) changes, assessed the differences in the ability to perform activities of daily living (ADL) scores of the patients in the two groups before treatment as well as at 7d and 14d of treatment, and counted the incidence of VTE, pressure pain, and superficial varicose veins in the two groups.Results There was no difference in the comparison of D-D, FIB, APTT, PT, and inflammation indexes between the two groups before treatment (P>0.05). D-D, FIB, IL-6, ICAM-1, TNF-α of both groups in 7d and 14d of treatment were lower than before treatment, and APTT and PT were higher than before treatment (P<0.05). D-D, FIB, IL-6, ICAM-1, and TNF-α in the electroacupuncture group were lower than those in the pressure band group for 7d and 14d of treatment (P<0.05). The APTT and PT of the electroacupuncture group were higher than that of the pressure band group in 7d of treatment (P<0.05), but there was no difference between the APTT and PT of the electroacupuncture group and the pressure band group in 14d of treatment (P>0.05). There was no difference in the comparison of ADL scores before treatment between the two groups (P>0.05). The ADL scores of 7d and 14d of treatment in both groups were higher than those before treatment (P<0.05), and the ADL scores of 7d and 14d of treatment in the electroacupuncture group were higher than those in the pressure band group (P<0.05). The incidence of VTE, the incidence of pressure pain, and the incidence of superficial varicose veins in the electroacupuncture group were lower than those in the pressure band group (P<0.05).Conclusion Electroacupuncture combined with antithrombotic compression taping can neurocritically ill patients at high risk for VTE, reduce the inflammatory response, improve coagulation, and decrease the incidence of VTE, compression pain, and superficial varicose veins.

  Key words: Electroacupuncture; Antithrombotic compression banding; Neurocritical care; High risk; Venous thromboembolism; Deep vein thrombosis

  Submit time: 31 March 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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