张颖, 余灵芝, 刘小英, 刘若婷, 秦茵. 基于喉镜吞咽功能评估的分层康复对卒中后吞咽障碍患者的疗效影响. 2025. biomedRxiv.202510.00033
基于喉镜吞咽功能评估的分层康复对卒中后吞咽障碍患者的疗效影响
通讯作者: 秦茵, baby792305220@163.com
DOI:10.12201/bmr.202510.00033
Efficacy of Stratified Rehabilitation Based on FEES Assessment in Patients with Post-Stroke Dysphagia
Corresponding author: QIN Yin, baby792305220@163.com
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摘要:目的 探讨基于喉镜吞咽功能评估(Fiberoptic Endoscopic Evaluation of Swallowing ,FEES)的吞咽障碍严重程度分层干预对卒中后吞咽障碍患者的疗效。方法 采用随机对照设计,纳入2024年6月—2025年6月中国人民解放军联勤保障部队第九〇〇医院收治的72例卒中后吞咽障碍患者,分为实验组和对照组。实验组根据FEES结合渗透误吸量(Penetration-Aspiration Scale, PAS)分为三级进行分层干预,对照组采用统一常规康复策略治疗,持续4周。比较两组患者吞咽功能改善程度,观察临床疗效。结果 干预4周后实验组总有效率显著优于对照组(P<0.05);两组患者渗透/误吸量表、吞咽功能、洼田饮水试验评分较基线期均显著降低(P<0.05),功能性经口摄食量表、生活质量量表评分较治疗前均显著升高(P<0.05),且实验组改善幅度显著优于对照组(P<0.05);治疗期间吸入性肺炎发生率实验组(2.8%)低于对照组(13.9%),差异无统计学意义(P=0.076)。结论 FEES-PAS指导的个性化分级干预对脑卒中后吞咽障碍疗效显著,能够有效促进患者吞咽功能恢复,具有临床推广价值。
Abstract: Objective To investigate the efficacy of a severity-graded intervention protocol for post-stroke dysphagia based on Fiberoptic Endoscopic Evaluation of Swallowing (FEES) assessment. Methods This randomized controlled trial enrolled 72 patients with post-stroke dysphagia admitted to the 900th Hospital of PLA Joint Logistics Support Force from June 2024 to June 2025. Participants were divided into an experimental group and a control group. The experimental group received a stratified intervention based on three levels determined by Fiberoptic Endoscopic Evaluation of Swallowing (FEES) combined with the Penetration-Aspiration Scale (PAS), while the control group received standardized conventional rehabilitation therapy. Both groups underwent 4 weeks of treatment. The improvement in swallowing function and clinical efficacy were compared between the two groups. Results After 4 weeks of intervention, the overall response rate in the experimental group was significantly higher than in the control group (P<0.05). Compared to baseline, both groups showed significant reductions in the Penetration-Aspiration Scale score, swallowing function scores, and Water Swallow Test score (P<0.05), while scores on the Functional Oral Intake Scale and the Quality of Life scale showed significant increases compared to pre-treatment levels (P<0.05). Furthermore, the experimental group demonstrated significantly greater improvements in all scales compared to the control group (P<0.05). During the treatment period, the incidence of aspiration pneumonia in the experimental group (2.8%) was lower than that in the control group (13.9%), but the difference was not statistically significant (P = 0.076). Conclusion FEES-PAS guided personalized graded intervention significantly improves swallowing function in post-stroke dysphagia patients, effectively promoting functional recovery and demonstrating substantial clinical value for broader application.
Key words: Stroke; Dysphagia; FEES;Individualized Rehabilitation;Graded intervention; ; ; ;提交时间:2025-10-20
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序号 提交日期 编号 操作 1 2025-10-10 bmr.202510.00033V1
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