宿纭溶, 樊明, 贺旭, 罗知琪. 《从“痰气并治”辨治肺结节探析——兼论〈金匮要略〉半夏厚朴汤的临床发挥》. 2026. biomedRxiv.202605.00101
《从“痰气并治”辨治肺结节探析——兼论〈金匮要略〉半夏厚朴汤的临床发挥》
通讯作者: 樊明, 845978962@qq.com
DOI:10.12201/bmr.202605.00101
Treating Pulmonary Nodules by Regulating Phlegm and Qi: A Discussion on the Clinical Use of Banxia Houpu Tang
Corresponding author: FANMING, 845978962@qq.com
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摘要:探讨基于“痰气并治”理论辨治肺结节(痰气互结证)的方证对应逻辑,并阐释《金匮要略》半夏厚朴汤通过“治气化痰”干预肺结节的临床拓展价值。基于中医经典理论与历代医家论述,分析肺结节“气郁为先导,痰凝为核心,瘀结为成形”的病理演变;结合典型临床病例,观察半夏厚朴汤加减对结节变化的干预作用。半夏厚朴汤辛开苦降,善行气散结、降逆化痰,直击痰气互结之病机。其组方暗合“治气即治痰”之法,通过温和气化阻断“气郁为先导、痰凝为核心、瘀结为成形”的病理进程。临床随证加减,不仅能稳定乃至缩小结节,且无明显毒副反应,彰显了“异病同治”的经方智慧,为肺结节的中医药干预提供了坚实的理论与临床支撑。
Abstract: This study aims to explore the formula-syndrome correspondence logic in differentiating and treating pulmonary nodules (phlegm-qi entanglement pattern) based on the theory of simultaneous treatment of phlegm and qi, and to elucidate the clinical extension value of Banxia Houpu Decoctionfrom the Jin Gui Yao Luein intervening in pulmonary nodules through regulating qi and resolving phlegm. Grounded in classical Traditional Chinese Medicine theories and historical medical texts, we analyzed the pathological evolution of pulmonary nodules characterized by qi stagnation as the precursor, phlegm coagulation as the core, and blood stasis as the formation. Through a typical clinical case, the intervention effect of modified Banxia Houpu Decoctionon nodule regression was observed. Banxia Houpu Decoction, endowed with pungent dispersion and bitter descent properties, excels at promoting qi circulation, dissipating masses, lowering adverse qi, and resolving phlegm, thereby directly targeting the pathogenesis of phlegm-qi entanglement. Its formulation implicitly aligns with the principle that treating qi equates to treating phlegm, effectively interrupting the pathological progression of qi stagnation – phlegm coagulation – stasis formation via mild qi transformation. Clinical modifications based on syndrome differentiation not only stabilized but also reduced nodule size without significant toxic side effects, demonstrating the clinical wisdom of treating different diseases with the same method and providing robust theoretical and clinical evidence for Traditional Chinese Medicine interventions in pulmonary nodules.
Key words: Pulmonary nodules; Phlegm-Qi entanglement pattern; Simultaneous treatment of phlegm and Qi; Banxia Houpu Decoction; Treating different diseases with the same method; Formula-syndrome correspondence提交时间:2026-05-28
版权声明:作者本人独立拥有该论文的版权,预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。 -
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序号 提交日期 编号 操作 1 2026-05-12 10.12201/bmr.202605.00101V1
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