通讯作者: 付丽, 23572515@qq.com

DOI：10.12201/bmr.202512.00023

Analysis of the association between the cardiometabolic index and diabetes in the elderly based on NHANES

• 摘要：【摘要】 目的 探讨心脏代谢指数(Cardiometabolic index，CMI)与老年糖尿病的关联。方法 基于2005-2018年美国国家健康与营养调查（National Health and Nutrition Examination Survey，NHANES）7个周期数据，纳入3769例参与者开展横断面研究。按是否患糖尿病分为两组。采用logistic回归分析CMI与糖尿病的关联，结合亚组分析、交互作用检验及ROC曲线分析。结果 总人群糖尿病患病率35.1%（1323/3769），总体 CMI为 0.57（0.35,0.94），糖尿病组 CMI为0.72（0.44，1.12），显著高于对照组 0.49（0.3，0.83)。调整多个混杂因素后，CMI升高与老年糖尿病患病风险独立相关（OR =1.504，95% CI 1.328～1.703，P<0.0001）。亚组分析及Bonferroni 校正显示，仅高血压亚组中CMI与糖尿病的关联存在交互作用（P交互＝0.0011＜0.0038）。其他亚组无显著交互作用（P交互作用＞0.05）。结论 CMI与老年糖尿病患病风险呈正相关，控制CMI水平或可降低老年人群的糖尿病发生风险。

  关键词： 糖尿病; 心脏代谢指数；横断面研究； NHANES; ; 

   

  Abstract: Abstract Objective Investigating the Relationship between the Cardiometabolic Index and Diabetes in the Elderly. Methods Based on data from seven cycles (2005–2018) of the National Health and Nutrition Examination Survey (NHANES), a cross-sectional study was conducted involving 3,769 participants. Participants were divided into two groups according to diabetes status. Logistic regression was used to analyze the association between CMI and diabetes, supplemented by subgroup analysis, interaction tests, and ROC curve analysis. Results The overall prevalence of diabetes was 35.1% (1323/3769). The median CMI in the total population was 0.57 (0.35, 0.94). The CMI in the diabetes group was 0.72 (0.44, 1.12), significantly higher than that in the control group 0.49 (0.30, 0.83). After adjusting for multiple confounding factors, elevated CMI was independently associated with an increased risk of diabetes in the elderly (OR = 1.504, 95% CI: 1.328–1.703, P < 0.0001). Subgroup analysis and Bonferroni correction revealed a significant interaction between CMI and diabetes only in the hypertension subgroup (P for interaction = 0.0011 < 0.0038). Conclusion CMI is positively associated with the risk of diabetes in the elderly. Controlling CMI levels may help reduce the risk of diabetes in the elderly. Key words ?Diabetes Cardiometabolic Index Cross-Sectional Study NHANE

  Key words: Diabetes; Cardiometabolic Index; Cross-Sectional; Study? NHANES

  提交时间：2025-12-10

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• 序号	提交日期	编号	操作
  1	2025-10-23	10.12201/bmr.202512.00023V1	下载

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