Observation of the Clinical Efficacy of Repetitive Transcranial Magnetic Stimulation in the Treatment of Functional Constipation

DOI: 10.12201/bmr.202511.00010

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  Abstract: Objective: To explore the efficacy of magnetic stimulation in the treatment of functional constipation. Methods: A total of 60 FC patients were selected from March 2022 to March 2023 who were diagnosed and treated in the outpatient clinic of the Department of Proctology of Nanjing Hospital of Traditional Chinese Medicine. They were randomly divided into experimental group and control group, with 30 cases in each group. The experimental group performed magnetic stimulation by placing the longitudinal axis of the coil at a 45° angle to the head, while the control group placed the vertical axis of the coil at a 90° angle to the skull. The evaluation scales and HRAM-related indicators of the two groups were compared. Results: The PAC-QOL, CSS, HAMA and HAMD were statistically significant before and after treatment in the experimental group (P<0.05), while the PAC-QOL, CSS, HAMA and HAMD in the control group were not statistically significant before and after treatment (P>0.05). AMSP, FSV and MTV were statistically significant in the experimental group (P<0.05), and ARP was not statistically significant (P>0.05). Only FSV was statistically significant in the control group (P<0.05), and the rest were not statistically significant. The RAIR, RAIR relaxation rate and RAIR relaxation time were statistically significant in the experimental group (P<0.05), and there was no statistically significant RAIR residual pressure (P>0.05). Conclusion: Magnetic stimulation in the treatment of functional constipation has a definite efficacy, which can relieve clinical symptoms, improve mental state, and improve HRAM-related indicators, which is worthy of promotion.

  Key words: functional constipation; magnetic stimulation; high-resolution anorectal manometry

  Submit time: 5 November 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
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