Based on the principle of Treating the middle jiao as balance to discuss the mechanism of action of Banxia Xingxin decoction in the treatment of functional dyspepsia

Corresponding author: Chen Jie, chenjie_zy@126.com

DOI: 10.12201/bmr.202508.00032

•  

  Abstract: Functional dyspepsia is a common functional disease of the gastrointestinal tract, which is believed to be caused by spleen deficiency and stagnation of qi, loss of gastric harmony, and imbalance of the elevation of qi in the middle jiao. Wu Jutong, a doctor in the Qing Dynasty, proposed the theory of “treating the middle jiao as balance” as a treatment principle for spleen and stomach diseases. This article discusses the pathogenesis of functional dyspepsia from the “middle jiao imbalance”, including the imbalance of elevation and descent, the imbalance of yin and yang, and the imbalance of zang and diarrhea. Banxia Xiexin Decoction regulates qi and restores the physiological functions of the spleen and stomach through the use of pungent, bitter and bitter remedies, the equalization of cold and heat, and the balance between deficiency and solidity, which is in line with the theoretical idea of “treating the middle jiao as balance”. Therefore, this article discusses the pathogenesis of functional dyspepsia based on the theory of “treating the middle jiao as balance” and the mechanism of action of Banxia Xiexin Decoction in treating functional dyspepsia, so as to provide more theoretical basis and ideas for the clinical research and treatment of functional dyspepsia.

  Key words: Treating middle Jiao as balance; Banxia Xiexin Decoction; Functional Dyspepsia; Mechanism of Action

  Submit time: 13 August 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• 李泽明, zhoujianyong, chentingting, wangcheng, liuzhenkun, qimei, lvjiling. Exploring the mechanism of Xiaochaihu Decoction in treating cough variant asthma (CVA) based on network pharmacology and animal experiments. 2025. doi: 10.12201/bmr.202510.00009

  . 2025. doi: 10.12201/bmr.202508.00034

  郭玥, WANG Xu. Treatment of systemic lupus erythematosus based on the principle of “treating the balance of power and weights and removing the chopsticks of Wan Chan”. 2025. doi: 10.12201/bmr.202506.00014

  WangJing. Research progress of Xiangsha Liujunzi Tang in digestive system diseases. 2025. doi: 10.12201/bmr.202503.00015

  Zhang Han, Chu Mengyuan, Xu Kaikai, Xiang Xin, Yan Ying. Progress in Mechanism of Action of Isthmin1 Protein in Polycystic Ovary Syndrome. 2024. doi: 10.12201/bmr.202411.00004

  wuwan, liuzhenzhong, zhaolijuan, penweixian. Exploring the Application Value of Sini Decoction in Treating Sepsis Based on the Theory of Acute Deficiency Syndrome. 2025. doi: 10.12201/bmr.202507.00012

  Liu Jinjing, Zhou Bowen, Yanmeijun, Li XiaoLi, Hao Shulan, Liu Likun. Professor Liu Likun experience in Treating Opioid relatedConstipation in Cancer Patients Based on the Three Jiao Differentiation. 2025. doi: 10.12201/bmr.202504.00042

  CHENG Yanyan, HE Jiayu, RUAN Yuhe, LI Zixin, ZHANG Ying. Exploration of the medication rules and mechanism of traditional Chinese medicine in treatment of cancer-related insomnia based on data mining, network pharmacology and molecular dynamics simulation.. 2025. doi: 10.12201/bmr.202510.00051

  wanggang, duyonghong. Analyzing the mechanism and treatment of diminished ovarian reserve based on the Chong and Ren theory. 2025. doi: 10.12201/bmr.202503.00034

• ID	Submit time	Number	Download
  1	2025-06-30	10.12201/bmr.202508.00032V1	Download

• Public  Anonymous  To author only Submit Comments