Based on data mining and network pharmacology, this paper explores the medication rules of traditional Chinese medicine in the treatment of senile deafness

Corresponding author: LU Lingjuan, 13367819383@163.com

DOI: 10.12201/bmr.202506.00077

•  

  Abstract: Objective: To explore the prescription and medication pattern and potential mechanism of action of traditional Chinese medicine (TCM) in the treatment of age-related deafness (ARHL) based on data mining and network pharmacology.Methods: through the China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, VIP,selected since the opening of the library of the literature of Chinese medicine treatment of ARHL through the use of Excel2019, Spss Statistics25, Spss Modeler18.0 for statistical analysis, the use of R4.4.2 for the visual analysis of the law of compounding medication in the literature ,The core drug combinations were screened out.The intersecting targets of TCM and diseases were obtained from TCMSP, GeneCards and other databases, and the drug-component-target network was constructed by using Cytoscape software to obtain the core targets and analyzed by GO and KEGG enrichment in DAVID database. The core targets were obtained and analyzed by GO and KEGG enrichment in DAVID database

  Key words: :age-related deafness; Traditional Chinese medicine; Data mining; Network pharmacology

  Submit time: 26 June 2025

  Copyright: The copyright holder for this preprint is the author/funder, who has granted biomedRxiv a license to display the preprint in perpetuity.
• html

• 图表

• CHENG Yanyan, HE Jiayu, RUAN Yuhe, LI Zixin, ZHANG Ying. Exploration of the medication rules and mechanism of traditional Chinese medicine in treatment of cancer-related insomnia based on data mining, network pharmacology and molecular dynamics simulation.. 2025. doi: 10.12201/bmr.202510.00051

  Wei Chunshan. Exploring medication rules and mechanism for liver cancer based on data mining and network pharmacology. 2024. doi: 10.12201/bmr.202407.00040

  chenqin. Analysis of the medication rules of famous traditional Chinese medicine practitioners for the treatment of Idiopathic Membranous Nephropathy based on data mining. 2025. doi: 10.12201/bmr.202507.00050

  刘永珍, Wang ling, Liu Fu Ron. Medication patterns of traditional Chinese medicine in the treatment of radiotherapy-induced oral mucositis:A study based on data mining. 2025. doi: 10.12201/bmr.202504.00049

  lidongfang. The Experience of Treating Age-related Gastric Cancer by National Master of Traditional Chinese Medicine Pan Minqiu. 2025. doi: 10.12201/bmr.202509.00069

  jinhui, xuhaoran, qiyahan, zengjingqi. Data Mining-Based Study on the Medication Rules of Renowned Chinese Medicine Practitioners in Treating Back Pain?. 2025. doi: 10.12201/bmr.202510.00020

  Yuan Zhenzhong. Mechanism of Relieves insomnia Effect of Jiaotai Pills Based on Network Pharmacology. 2024. doi: 10.12201/bmr.202408.00069

  WANG Xiaoyan, LIU Liping, KOANG Lingxia, ZHENG Xiaojuan, CHUN Zhuo. Exploring the Medication Patterns of Pediatric Night Cough Treatment Based on the Shaoyang Pivot Theory through Data Mining. 2025. doi: 10.12201/bmr.202502.00014

  LI Suping, HONG Suru, WU Xiayang. Based on network pharmacology and molecular docking technology to explore the molecular mechanism of Oulongma oral drops in the treatment of allergic rhinitis. 2025. doi: 10.12201/bmr.202508.00023

  Wang Ken, Jiao Qingfang, Long Wenling, Zhang Zhen, Wang Hong, Yang Wanquan. Clinical efficacy and mechanism of Shenqi Shiyiwei granules in cancer-related anemia of Colon cancer based on network pharmacology. 2025. doi: 10.12201/bmr.202506.00080

• ID	Submit time	Number	Download
  1	2025-06-07	10.12201/bmr.202506.00077V1	Download

• Public  Anonymous  To author only Submit Comments