通讯作者: 张再兴, 3350376095@qq.com

DOI：10.12201/bmr.202511.00017

• 摘要：鼻中隔黏膜恶性黑色素瘤的病例极为少见，且易误诊，若能早期识别并加以干预，可改善患者预后。本文报道1例鼻中隔黏膜恶性黑色素瘤患者并进行相关文献复习，以期提高临床医师对其的认识，减少因误诊及延误病情造成的不良后果。

   

  Abstract: Objective To explore the clinical manifestations, diagnostic criteria, imaging manifestations, postoperative pathological features and surgery in the treatment of malignant melanoma of the nasal septum mucosa and to reduce clinical misdiagnosis and leakage. Methods? We retrospectively analyzed the case data of a patient with malignant melanoma of the nasal septum mucosa admitted to the North China University of Science and Technology Affiliated Hospital in August 2024 and summarized the results by analyzing clinical features, imaging manifestations, diagnostic criteria postoperative pathological features and treatment methods, and reviewing the relevant literature. Results? A 66-year-old male patient presented with? nasal obstruction and epistaxis and the imaging manifestations were nonspecific. After surgical excision, the pathological findings confirmed the diagnosis of malignant melanoma of the nasal septum mucosa. Due to its highly aggressive nature, the patient underwent standardized postoperative radiotherapy and chemotherapy with close follow-up. Conclusion? Malignant melanoma of the nasal septum mucosa is a rare diseases with low incidence, lack of typical clinical manifestations and specific imaging features, and mostly cannot be clearly diagnosed preoperatively. Pathological examination is important in the diagnosis of the disease, and surgical intervention combined with radiotherapy and chemotherapy serves as an effective therapeutic approach for this condition.

  提交时间：2025-11-10

  版权声明：作者本人独立拥有该论文的版权，预印本系统仅拥有论文的永久保存权利。任何人未经允许不得重复使用。
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• 序号	提交日期	编号	操作
  1	2025-07-24	10.12201/bmr.202511.00017V1	下载

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